Anti-Phospho-STAT3 (pY705) Recombinant Antibody (SAA0302) (HW708010)

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100ug
1mg

数量：

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概述
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参考文献
产品说明书

概述

货号	HW708010
品牌	abinScience
描述	InVivoMAb Anti-Human STAT3 Antibody (Iv0126) [Iv0126] (HW708010) is a human monoclonal antibody detecting Signal transducer and activator of transcription 3 in ELISA, FCM, Neutralization. Suitable for Human. Highlights ●Multi-Application — Validated across multiple applications. ●Flow Cytometry — Validated for flow cytometry applications.
种属反应性	Human
应用	ELISA, FCM, Neutralization
宿主	Human
克隆类型	Monoclonal
同种型	VHH-hFc
克隆号	Iv0126
经测试应用	FCM
靶标	Signal transducer and activator of transcription 3, APRF, STAT3, Acute-phase response factor
内毒素水平	< 10 EU/mg as determined by LAL method.
纯度	>95% as determined by SDS-PAGE.
相关产品	pH 7.4 Dilution Buffer
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P40763
状态	Liquid
保存溶液	0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	Signal transducer and activator of transcription 3 (p-STAT3) is a ~88 kDa protein. Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors. Once activated, recruits coactivators, such as NCOA1 or MED1, to the promoter region of the target gene. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Upon activation of IL6ST/gp130 signaling by interleukin-6 (IL6), binds to the IL6-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA. 1. Tsai, YT. et al. (2000) Molecular and cellular biology 20, 2043-54. PMID: 10688651 2. Yamamoto, T. et al. (2002) Biochemical and biophysical research communications 297, 811-7. PMID: 12359225 3. Shao, H. et al. (2003) Cancer research 63, 3923-30. PMID: 12873986 4. Dreuw, A. et al. (2004) The Journal of biological chemistry 279, 36112-20. PMID: 15194700 5. Yuan, ZL. et al. (2005) Science (New York, N.Y.) 307, 269-73. PMID: 15653507 6. Ray, S. et al. (2005) Gastroenterology 129, 1616-32. PMID: 16285960 7. Saxena, NK. et al. (2007) The Journal of biological chemistry 282, 13316-25. PMID: 17344214 8. Jiang, H. et al. (2008) Biochemical and biophysical research communications 368, 1-5. PMID: 18242580 9. Hou, T. et al. (2008) The Journal of biological chemistry 283, 30725-34. PMID: 18782771 10. Gao, X. et al. (2012) Molecular cell 45, 598-609. PMID: 22306293
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

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Flow Cytometry

Flow-cytometry using anti-human STAT3 antibody.HepG2 cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human STAT3 antibody monoclonal antibody (Catalog # HW708010 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-human antibody (Catalog # HF690414) and cells analysed on a NovoCyte Flow Cytometer.
Flow Cytometry

Flow-cytometry using anti-human STAT3 antibody.Human Jurkat cell line were stained with an irrelevant antibody (Blue Histogram) or an anti-human STAT3 antibody monoclonal antibody (Catalog # HW708010 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-human antibody (Catalog # HF690414) and cells analysed on a NovoCyte Flow Cytometer.
Flow Cytometry

Flow-cytometry using anti-human STAT3 antibody.A431 cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human STAT3 antibody monoclonal antibody (Catalog # HW708010 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-human antibody (Catalog # HF690414) and cells analysed on a NovoCyte Flow Cytometer.
Flow Cytometry

Flow-cytometry using anti-human STAT3 antibody.HeLa cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human STAT3 antibody monoclonal antibody (Catalog # HW708010 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-human antibody (Catalog # HF690414) and cells analysed on a NovoCyte Flow Cytometer.

参考文献

产品说明书

Anti-Phospho-STAT3 (pY705) Recombinant Antibody (SAA0302).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

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质量

浓度

体积

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g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

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Anti-Phospho-STAT3 (pY705) Recombinant Antibody (SAA0302) (HW708010)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Phospho-STAT3 (pY705) Recombinant Antibody (SAA0302) (HW708010)

概述

图片

参考文献

产品说明书

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