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Anti-Human Tau Recombinant Antibody (KW1) (HY086133)

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规格:
  • 50ug
  • 100ug
  • 1mg
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  • 概述

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  • 产品说明书

概述
货号HY086133
品牌abinScience
描述
Anti-Human Tau Recombinant Antibody (KW1) (HY086133) is a human monoclonal antibody detecting Tau in Blocking, ELISA. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
种属反应性Human
应用Blocking, ELISA
宿主Human
克隆类型Monoclonal
同种型VHH-Fc
克隆号KW1
靶标MAPT, MAPTL, MTBT1, Microtubule-associated protein tau, Neurofibrillary tangle protein, PHF-tau, Paired helical filament-tau, TAU
内毒素水平< 10 EU/mg as determined by LAL method.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P10636
RRIDAnti-Human MAPT/Tau/PHF-tau Antibody (KW1) (abinScience Cat# HY086133, RRID:AB_3725856)
状态Liquid
保存溶液 0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:2000-1:20000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Microtubule-associated protein tau (MAPT) is a ~78 kDa protein. Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

1. Yoshida, H. et al. (2012) Journal of neurochemistry 120, 165-76. PMID: 21985311
2. Sandberg, A. et al. (2020) Neurobiology of disease 146, 105079. PMID: 32961270
NoteFor research use only.
Isotype ControlVHH-hFc (IgG1) Isotype Control antibody (cAb-Lys2) (ZP167307)
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Human MAPT/Tau/PHF-tau Antibody (KW1).

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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