

| 货号 | HX949013 | ||||||
|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||
| 描述 |
Anti-Human NAP1L1 Nanobody (SAA1229) [SAA1229] (HX949013) is a alpaca monoclonal antibody detecting NAP1L1 in ELISA, IP, WB. Suitable for Human.
Highlights
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| 种属反应性 | Human | ||||||
| 应用 | ELISA, IP, WB | ||||||
| 宿主 | Alpaca | ||||||
| 克隆类型 | Monoclonal | ||||||
| 同种型 | VHH-8His-Cys-tag | ||||||
| 克隆号 | SAA1229 | ||||||
| 靶标 | NAP-1-related protein, NRP, hNRP, Nucleosome assembly protein 1-like 1, NAP1L1 | ||||||
| 内毒素水平 | < 10 EU/mg as determined by LAL method. | ||||||
| 纯度 | >95% as determined by SDS-PAGE. | ||||||
| 纯化方式 | Purified by Nickel column. | ||||||
| Accession号 | P55209 | ||||||
| 状态 | Liquid | ||||||
| 保存溶液 | 0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||
| 背景 | Nucleosome assembly protein 1-like 1 (NAP1L1) is a ~45 kDa protein. Histone chaperone that plays a role in the nuclear import of H2A-H2B and nucleosome assembly. Also participates in several important DNA repair mechanisms: greatly enhances ERCC6-mediated chromatin remodeling which is essential for transcription-coupled nucleotide excision DNA repair. Also stimulates homologous recombination (HR) by RAD51 and RAD54 which is essential in mitotic DNA double strand break (DSB) repair. Plays a key role in the regulation of embryonic neurogenesis. Promotes the proliferation of neural progenitors and inhibits neuronal differentiation during cortical development. 1. Okuwaki, M. et al. (2010) Genes to cells : devoted to molecular & cellular mechanisms 15, 13-27. PMID: 20002496 2. Mehrotra, PV. et al. (2011) Molecular cell 41, 46-55. PMID: 21211722 3. Ohtomo, H. et al. (2016) Genes to cells : devoted to molecular & cellular mechanisms 21, 252-63. PMID: 26841755 4. Lee, JY. et al. (2017) Nucleic acids research 45, 4696-4707. PMID: 28369616 5. Machida, S. et al. (2014) Scientific reports 4, 4863. PMID: 24798879 | ||||||
| Note | For research use only. |

SDS-PAGE for Anti-Human NAP1L1 Nanobody (SAA1229)



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