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Anti-Human NAP1L1 Polyclonal Antibody (ARO-A12006)

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概述
货号ARO-A12006
品牌ProteoGenix
描述
Anti-Human NAP1L1 Polyclonal Antibody (ARO-A12006) is a rabbit polyclonal antibody detecting NAP-1-related protein, NRP, hNRP, Nucleosome assembly protein 1-like 1, NAP1L1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human NAP1L1 (Arg72-Glu356).
靶标NAP-1-related protein, NRP, hNRP, Nucleosome assembly protein 1-like 1, NAP1L1
纯化方式Purified by antigen affinity column.
Accession号P55209
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Nucleosome assembly protein 1-like 1 (NAP1L1) is a ~45 kDa protein. Histone chaperone that plays a role in the nuclear import of H2A-H2B and nucleosome assembly. Also participates in several important DNA repair mechanisms: greatly enhances ERCC6-mediated chromatin remodeling which is essential for transcription-coupled nucleotide excision DNA repair. Also stimulates homologous recombination (HR) by RAD51 and RAD54 which is essential in mitotic DNA double strand break (DSB) repair. Plays a key role in the regulation of embryonic neurogenesis. Promotes the proliferation of neural progenitors and inhibits neuronal differentiation during cortical development.

1. Okuwaki, M. et al. (2010) Genes to cells : devoted to molecular & cellular mechanisms 15, 13-27. PMID: 20002496
2. Mehrotra, PV. et al. (2011) Molecular cell 41, 46-55. PMID: 21211722
3. Ohtomo, H. et al. (2016) Genes to cells : devoted to molecular & cellular mechanisms 21, 252-63. PMID: 26841755
4. Lee, JY. et al. (2017) Nucleic acids research 45, 4696-4707. PMID: 28369616
5. Machida, S. et al. (2014) Scientific reports 4, 4863. PMID: 24798879
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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