

| 货号 | ARO-A12006 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-Human NAP1L1 Polyclonal Antibody (ARO-A12006) is a rabbit polyclonal antibody detecting NAP-1-related protein, NRP, hNRP, Nucleosome assembly protein 1-like 1, NAP1L1 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 同种型 | IgG |
| 克隆类型 | Polyclonal |
| 免疫原 | E. coli - derived recombinant Human NAP1L1 (Arg72-Glu356). |
| 靶标 | NAP-1-related protein, NRP, hNRP, Nucleosome assembly protein 1-like 1, NAP1L1 |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | P55209 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Nucleosome assembly protein 1-like 1 (NAP1L1) is a ~45 kDa protein. Histone chaperone that plays a role in the nuclear import of H2A-H2B and nucleosome assembly. Also participates in several important DNA repair mechanisms: greatly enhances ERCC6-mediated chromatin remodeling which is essential for transcription-coupled nucleotide excision DNA repair. Also stimulates homologous recombination (HR) by RAD51 and RAD54 which is essential in mitotic DNA double strand break (DSB) repair. Plays a key role in the regulation of embryonic neurogenesis. Promotes the proliferation of neural progenitors and inhibits neuronal differentiation during cortical development. 1. Okuwaki, M. et al. (2010) Genes to cells : devoted to molecular & cellular mechanisms 15, 13-27. PMID: 20002496 2. Mehrotra, PV. et al. (2011) Molecular cell 41, 46-55. PMID: 21211722 3. Ohtomo, H. et al. (2016) Genes to cells : devoted to molecular & cellular mechanisms 21, 252-63. PMID: 26841755 4. Lee, JY. et al. (2017) Nucleic acids research 45, 4696-4707. PMID: 28369616 5. Machida, S. et al. (2014) Scientific reports 4, 4863. PMID: 24798879 |
| Note | For research use only. |

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