Anti-Human IL-17RA/IL-17R Recombinant Nanobody (SAA1266) (HV263013)

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50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

概述

货号

HV263013

品牌

abinScience

描述

Anti-Human CD217/IL17RA Nanobody (SAA1266) [SAA1266] (HV263013) is a alpaca monoclonal antibody detecting IL17RA in ELISA. Suitable for Human.

种属反应性

Human

应用

ELISA

宿主

Alpaca

克隆类型

Monoclonal

同种型

VHH-8His-Cys-tag

克隆号

SAA1266

经测试应用

靶标

IL17R, CDw217, IL-17RA, Interleukin-17 receptor A, IL-17 receptor A, IL17RA, CD217

内毒素水平

< 10 EU/mg as determined by LAL method.

纯度

>95% as determined by SDS-PAGE.

纯化方式

Purified by Nickel column.

Accession号

Q96F46

状态

Liquid

保存溶液

0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Interleukin-17 receptor A (CD217/IL17RA) is a ~96 kDa protein. Receptor for IL17A and IL17F, major effector cytokines of innate and adaptive immune system involved in antimicrobial host defense and maintenance of tissue integrity. Receptor for IL17A. Receptor for IL17F. Binds to IL17A with higher affinity than to IL17F. Binds IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RC.

1. Kuestner, RE. et al. (2007) Journal of immunology (Baltimore, Md. : 1950) 179, 5462-73. PMID: 17911633

2. Yao, Z. et al. (1997) Cytokine 9, 794-800. PMID: 9367539

3. Ely, LK. et al. (2009) Nature immunology 10, 1245-51. PMID: 19838198

4. Toy, D. et al. (2006) Journal of immunology (Baltimore, Md. : 1950) 177, 36-9. PMID: 16785495

5. Wright, JF. et al. (2008) Journal of immunology (Baltimore, Md. : 1950) 181, 2799-805. PMID: 18684971

6. Puel, A. et al. (2011) Science (New York, N.Y.) 332, 65-8. PMID: 21350122

7. Boisson, B. et al. (2013) Immunity 39, 676-86. PMID: 24120361

Note

For research use only.

图片

SDS-PAGE

SDS-PAGE for Anti-Human CD217/IL17RA Nanobody (SAA1266)
Bioactivity

Detects recombinant CD217 (Catalog No: HV263011) in indirect ELISA.
Immunofluorescence

Immunofluorescence staining of Hepg2 with Alpaca monoclonal antibody (20ug/ml, overnight at 4°C), followed by Alexa Fluor-488-conjugated secondary antibody (6.5ug/ml, 50minutes at room temperature). The target protein was detected in the Cell membrane,Secreted.
Immunofluorescence

Immunofluorescence staining of THP1 with Alpaca monoclonal antibody (20ug/ml, overnight at 4°C), followed by Alexa Fluor-488-conjugated secondary antibody (6.5ug/ml, 50minutes at room temperature). The target protein was detected in the Cell membrane,Secreted.

参考文献

产品说明书

Anti-Human IL-17RA/IL-17R Recombinant Nanobody (SAA1266).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human IL-17RA/IL-17R Recombinant Nanobody (SAA1266) (HV263013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human IL-17RA/IL-17R Recombinant Nanobody (SAA1266) (HV263013)

概述

图片

参考文献

产品说明书

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