Anti-Mouse TRANCE/TNFSF11/RANK L Recombinant Antibody (7C6) (MT439013)

价格:

规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

MT439013

abinScience

种属反应性

Mouse

ELISA

IgG2a, kappa

TNFSF11, OPGL, ODF, RANKL, TRANCE, Tumor necrosis factor ligand superfamily member 11, Osteoclast differentiation factor, Osteoprotegerin ligand, Receptor activator of nuclear factor kappa-B ligand, TNF-related activation-induced cytokine, CD254

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

O35235

Anti-Mouse CD254/RANKL/TNFSF11 Antibody (7C6) (abinScience Cat# MT439013, RRID:AB_3727125)

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Tumor necrosis factor ligand superfamily member 11 (CD254/RANKL) is a ~35 kDa protein. Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy. CD254 is the therapeutic target of denosumab (Prolia).

1. Linares, GR. et al. (2012) Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 27, 1553-65. PMID: 22437732

2. Mahoney, DJ. et al. (2008) The Journal of biological chemistry 283, 25952-62. PMID: 18586671

3. Tiedemann, K. et al. (2013) Journal of cell science 126, 4187-94. PMID: 24039232

4. Omata, Y. et al. (2016) PloS one 11, e0157992. PMID: 27336669

5. Kim, H. et al. (2013) Cell metabolism 17, 249-60. PMID: 23395171

6. Decker, CE. et al. (2015) Proceedings of the National Academy of Sciences of the United States of America 112, 15654-9. PMID: 26644563

For research use only.

SDS-PAGE

SDS-PAGE for Anti-Mouse CD254/RANKL/TNFSF11 Antibody (7C6)

产品说明书

Anti-Mouse TRANCE/TNFSF11/RANK L Recombinant Antibody (7C6).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse TRANCE/TNFSF11/RANK L Recombinant Antibody (7C6) (MT439013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse TRANCE/TNFSF11/RANK L Recombinant Antibody (7C6) (MT439013)

概述

图片

参考文献

产品说明书

相关产品推荐

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