InVivoMAb Anti-Human MASP2 Antibody (17D20) (HT020010)

价格:

规格：

100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

概述

货号

HT020010

品牌

abinScience

描述

InVivoMAb Anti-Human MASP2 Antibody (17D20) [17D20] (HT020010) is a human monoclonal antibody detecting Mannan-binding lectin serine protease 2 in ELISA, FCM. Suitable for Human.

Highlights

●Flow Cytometry — Validated for flow cytometry applications.

种属反应性

Human

应用

ELISA, FCM, Block

宿主

Human

同种型

IgG4, lambda

克隆号

17D20

克隆类型

Monoclonal

靶标

Mannan-binding lectin serine protease 2, Mannose-binding protein-associated serine protease 2, MASP-2, MBL-associated serine protease 2, MASP2

内毒素水平

Please contact with the lab for this information.

纯度

>95% as determined by SDS-PAGE.

相关产品

pH 7.4 Dilution Buffer

纯化方式

Protein A/G purified from cell culture supernatant.

Accession号

O00187

状态

Liquid

保存溶液

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

重悬

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Mannan-binding lectin serine protease 2 (MASP2) is a ~75 kDa protein. Precursor of a serum protease that activates the lectin pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. The lectin complement system is activated following association of lectins, such as MBL2, FCN1, FCN2 or FCN3, to carbohydrates on the pathogen surface. MASP2 is cleaved and activated by MASP1 in response to lectin-binding to pathogen carbohydrates. Can activate prothrombin to thrombin.

1. Rossi, V. et al. (2001) The Journal of biological chemistry 276, 40880-7. PMID: 11527969

2. Héja, D. et al. (2012) Proceedings of the National Academy of Sciences of the United States of America 109, 10498-503. PMID: 22691502

3. Degn, SE. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 189, 3957-69. PMID: 22966085

4. Matsushita, M. et al. (2000) Journal of immunology (Baltimore, Md. : 1950) 165, 2637-42. PMID: 10946292

5. Kidmose, RT. et al. (2012) Proceedings of the National Academy of Sciences of the United States of America 109, 15425-30. PMID: 22949645

6. Thiel, S. et al. (1997) Nature 386, 506-10. PMID: 9087411

7. Valenzuela Leon, PC. et al. (2025) Journal of medicinal chemistry 68, 4663-4671. PMID: 39924859

Note

For research use only. Not suitable for clinical or therapeutic use.

图片

SDS-PAGE

SDS-PAGE for InVivoMAb Anti-Human MASP2 Antibody (17D20).

参考文献

产品说明书

InVivoMAb Anti-Human MASP2 Antibody (17D20).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

InVivoMAb Anti-Human MASP2 Antibody (17D20) (HT020010)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

InVivoMAb Anti-Human MASP2 Antibody (17D20) (HT020010)

概述

图片

参考文献

产品说明书

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