Anti-Human KCNK9 Recombinant Antibody (SAA1716) (HV232013)

价格:

规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HV232013

abinScience

种属反应性

Human

ELISA

IgG2a, kappa

SAA1716

TASK3, KCNK9, Acid-sensitive potassium channel protein TASK-3, Potassium channel subfamily K member 9, Two pore K(+) channel KT3.2, TWIK-related acid-sensitive K(+) channel 3, Two pore potassium channel KT3.2

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

Q9NPC2

Anti-Human KCNK9 Antibody (SAA1716) (abinScience Cat# HV232013, RRID:AB_3727477)

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Potassium channel subfamily K member 9 (KCNK9) is a ~42 kDa protein. K(+) channel that conducts voltage-dependent outward rectifying currents upon membrane depolarization. Voltage sensing is coupled to K(+) electrochemical gradient in an 'ion flux gating' mode where outward but not inward ion flow opens the gate. Changes ion selectivity and becomes permeable to Na(+) ions in response to extracellular acidification. Protonation of the pH sensor His-98 stabilizes C-type inactivation conformation likely converting the channel from outward K(+)-conducting, to inward Na(+)-conducting to nonconductive state. Homo- and heterodimerizes to form functional channels with distinct regulatory and gating properties.

1. Chapman, CG. et al. (2000) Brain research. Molecular brain research 82, 74-83. PMID: 11042359

2. Vega-Saenz de Miera, E. et al. (2001) Journal of neurophysiology 86, 130-42. PMID: 11431495

3. Schewe, M. et al. (2016) Cell 164, 937-49. PMID: 26919430

4. Lin, H. et al. (2024) Proceedings of the National Academy of Sciences of the United States of America 121, e2320345121. PMID: 38630723

5. Ma, L. et al. (2012) The Journal of biological chemistry 287, 37145-53. PMID: 22948150

6. Plant, LD. et al. (2012) Science signaling 5, ra84. PMID: 23169818

For research use only.

SDS-PAGE

SDS-PAGE for Anti-Human KCNK9 Antibody (SAA1716)

产品说明书

Anti-Human KCNK9 Recombinant Antibody (SAA1716).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human KCNK9 Recombinant Antibody (SAA1716) (HV232013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human KCNK9 Recombinant Antibody (SAA1716) (HV232013)

概述

图片

参考文献

产品说明书

相关产品推荐

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