

| 货号 | HP148013 | ||||
|---|---|---|---|---|---|
| 品牌 | abinScience | ||||
| 种属反应性 | Human | ||||
| 应用 | ELISA | ||||
| 同种型 | IgG2a, kappa | ||||
| 克隆号 | SAA1725 | ||||
| 靶标 | ING4, Inhibitor of growth protein 4, p29ING4 | ||||
| 内毒素水平 | Please contact with the lab for this information. | ||||
| 纯度 | >95% as determined by SDS-PAGE. | ||||
| 纯化方式 | Protein A/G purified from cell culture supernatant. | ||||
| Accession号 | Q9UNL4 | ||||
| RRID | Anti-Human ING4 Antibody (SAA1725) (abinScience Cat# HP148013, RRID:AB_3727486) | ||||
| 状态 | Liquid | ||||
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Inhibitor of growth protein 4 (ING4) is a ~28 kDa protein. Component of HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys-14' (H3K14ac), and have reduced activity toward histone H4. Through chromatin acetylation it may function in DNA replication. May inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation. Can suppress brain tumor angiogenesis through transcriptional repression of RELA/NFKB3 target genes when complexed with RELA. May also specifically suppress loss of contact inhibition elicited by activated oncogenes such as MYC. 1. Doyon, Y. et al. (2006) Molecular cell 21, 51-64. PMID: 16387653 2. Zhang, X. et al. (2004) FEBS letters 570, 7-12. PMID: 15251430 3. Kim, S. et al. (2004) Proceedings of the National Academy of Sciences of the United States of America 101, 16251-6. PMID: 15528276 4. Garkavtsev, I. et al. (2004) Nature 428, 328-32. PMID: 15029197 5. Ozer, A. et al. (2005) Proceedings of the National Academy of Sciences of the United States of America 102, 7481-6. PMID: 15897452 | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Human ING4 Antibody (SAA1725)



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