Anti-Human SIRT5 Recombinant Antibody (SAA2132) (HP532023)

价格:

规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HP532023

abinScience

种属反应性

Human

ELISA, IF, IP

IgG2a

SAA2132

SIRT5, SIR2L5, NAD-dependent protein deacylase sirtuin-5, mitochondrial, Regulatory protein SIR2 homolog 5, SIR2-like protein 5

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

Q9NXA8

Anti-Human SIRT5 Antibody (SAA2132) (abinScience Cat# HP532023, RRID:AB_3729488)

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

NAD-dependent protein deacylase sirtuin-5, mitochondrial (SIRT5) is a ~33 kDa protein. NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Activates SHMT2 by mediating its desuccinylation. Modulates ketogenesis through the desuccinylation and activation of HMGCS2.

1. Peng, C. et al. (2011) Molecular & cellular proteomics : MCP 10, M111.012658. PMID: 21908771

2. Du, J. et al. (2011) Science (New York, N.Y.) 334, 806-9. PMID: 22076378

3. Tan, M. et al. (2014) Cell metabolism 19, 605-17. PMID: 24703693

4. Yang, X. et al. (2018) Cancer research 78, 372-386. PMID: 29180469

5. Lin, ZF. et al. (2013) Biochemical and biophysical research communications 441, 191-5. PMID: 24140062

For research use only.

SDS-PAGE

SDS-PAGE for Anti-Human SIRT5 Antibody (SAA2132)

产品说明书

Anti-Human SIRT5 Recombinant Antibody (SAA2132).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human SIRT5 Recombinant Antibody (SAA2132) (HP532023)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human SIRT5 Recombinant Antibody (SAA2132) (HP532023)

概述

图片

参考文献

产品说明书

相关产品推荐

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