



| 货号 | HY086253 | ||||
|---|---|---|---|---|---|
| 品牌 | abinScience | ||||
| 描述 |
Anti-Human MAPT/Tau/PHF-tau Nanobody (SAA2138) [SAA2138] (HY086253) is a alpaca monoclonal antibody detecting PHF-tau in ELISA. Suitable for Human.
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| 种属反应性 | Human | ||||
| 应用 | ELISA, FCM, IHC | ||||
| 宿主 | Alpaca | ||||
| 同种型 | VHH-8His-Cys-tag | ||||
| 克隆号 | SAA2138 | ||||
| 克隆类型 | Monoclonal | ||||
| 靶标 | Microtubule-associated protein tau, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau, MAPT, MAPTL, MTBT1, TAU | ||||
| 内毒素水平 | Please contact with the lab for this information. | ||||
| 纯度 | >95% as determined by SDS-PAGE. | ||||
| 纯化方式 | Purified by Nickel column | ||||
| Accession号 | P10636 | ||||
| 状态 | Liquid | ||||
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 重悬 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. | ||||
| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 背景 | Microtubule-associated protein tau (MAPT) is a ~78 kDa protein. Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. 1. Yoshida, H. et al. (2012) Journal of neurochemistry 120, 165-76. PMID: 21985311 2. Sandberg, A. et al. (2020) Neurobiology of disease 146, 105079. PMID: 32961270 | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Human MAPT/Tau/PHF-tau Nanobody (SAA2138).

Detects recombinatn tau protein (Catalog No: HY086012) in indirect ELISA.





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