Anti-Human CX3CR1 Recombinant Nanobody (11H11) (HW331023)

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50ug
100ug
1mg

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概述
图片
参考文献
产品说明书

概述

货号

HW331023

品牌

abinScience

描述

Anti-Human CX3CR1 Nanobody (11H11) [11H11] (HW331023) is a alpaca monoclonal antibody detecting CX3CR1 in ELISA. Suitable for Human.

种属反应性

Human

应用

ELISA

宿主

Alpaca

同种型

VHH-8His-Cys-tag

克隆号

11H11

克隆类型

Monoclonal

靶标

CX3CR1, Beta chemokine receptor-like 1, Fractalkine receptor, CMK-BRL1, GPR13, CMKBRL1, CX3C chemokine receptor 1, V28, G-protein coupled receptor 13, C-X3-C CKR-1, CMK-BRL-1

内毒素水平

Please contact with the lab for this information.

纯度

>95% as determined by SDS-PAGE.

纯化方式

Protein A/G purified from cell culture supernatant.

Accession号

P49238

状态

Liquid

保存溶液

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

CX3C chemokine receptor 1 (CX3CR1) is a ~40 kDa protein. Receptor for the C-X3-C chemokine fractalkine (CX3CL1) present on many early leukocyte cells; CX3CR1-CX3CL1 signaling exerts distinct functions in different tissue compartments, such as immune response, inflammation, cell adhesion and chemotaxis. CX3CR1-CX3CL1 signaling mediates cell migratory functions. Responsible for the recruitment of natural killer (NK) cells to inflamed tissues. Acts as a regulator of inflammation process leading to atherogenesis by mediating macrophage and monocyte recruitment to inflamed atherosclerotic plaques, promoting cell survival. Involved in airway inflammation by promoting interleukin 2-producing T helper (Th2) cell survival in inflamed lung.

1. Nishimura, M. et al. (2002) Journal of immunology (Baltimore, Md. : 1950) 168, 6173-80. PMID: 12055230

2. Fujita, M. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 189, 5809-19. PMID: 23125415

3. Imai, T. et al. (1997) Cell 91, 521-30. PMID: 9390561

4. Fong, AM. et al. (1998) The Journal of experimental medicine 188, 1413-9. PMID: 9782118

5. Lucas, AD. et al. (2003) Circulation 108, 2498-504. PMID: 14581400

6. Landsman, L. et al. (2009) Blood 113, 963-72. PMID: 18971423

7. Leonardi, I. et al. (2018) Science (New York, N.Y.) 359, 232-236. PMID: 29326275

8. Nakayama, T. et al. (2010) Journal of immunology (Baltimore, Md. : 1950) 185, 6472-9. PMID: 20974991

Note

For research use only.

图片

SDS-PAGE

SDS-PAGE for Anti-Human CX3CR1 Nanobody (11H11)

参考文献

产品说明书

Anti-Human CX3CR1 Recombinant Nanobody (11H11).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CX3CR1 Recombinant Nanobody (11H11) (HW331023)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CX3CR1 Recombinant Nanobody (11H11) (HW331023)

概述

图片

参考文献

产品说明书

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