

| 货号 | HF781033 | ||||||
|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||
| 种属反应性 | Human | ||||||
| 应用 | ELISA, IHC, WB | ||||||
| 同种型 | IgG2a, kappa | ||||||
| 克隆号 | LMab-1 | ||||||
| 靶标 | IDH1, IDH, NADP(+)-specific ICDH, Isocitrate dehydrogenase [NADP] cytoplasmic, PICD, IDP, Cytosolic NADP-isocitrate dehydrogenase, Oxalosuccinate decarboxylase | ||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||
| 纯度 | >95% as determined by SDS-PAGE. | ||||||
| 纯化方式 | Protein A/G purified from cell culture supernatant. | ||||||
| Accession号 | O75874 | ||||||
| RRID | Anti-Human IDH1-R132L-specific Antibody (LMab-1) (abinScience Cat# HF781033, RRID:AB_3729710) | ||||||
| 状态 | Liquid | ||||||
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||||
| 背景 | Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1-R132L-specific) is a ~46 kDa protein. Catalyzes the NADP(+)-dependent oxidative decarboxylation of isocitrate (D-threo-isocitrate) to 2-ketoglutarate (2-oxoglutarate), which is required by other enzymes such as the phytanoyl-CoA dioxygenase. Plays a critical role in the generation of NADPH, an important cofactor in many biosynthesis pathways. May act as a corneal epithelial crystallin and may be involved in maintaining corneal epithelial transparency. 1. Geisbrecht, BV. et al. (1999) The Journal of biological chemistry 274, 30527-33. PMID: 10521434 2. Dang, L. et al. (2009) Nature 462, 739-44. PMID: 19935646 | ||||||
| Note | For research use only. |

SDS-PAGE for Anti-Human IDH1-R132L-specific Antibody (LMab-1)



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