

| 货号 | HF781014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-IDH1 Polyclonal Antibody (HF781014) is a rabbit polyclonal antibody detecting IDH1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Microtus mexicanus.
Highlights
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| 种属反应性 | Human, Mouse, Rat | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Human IDH1 (Met1-Leu414). | ||||||||
| 靶标 | IDH1, IDH, NADP(+)-specific ICDH, Isocitrate dehydrogenase [NADP] cytoplasmic, PICD, IDP, Cytosolic NADP-isocitrate dehydrogenase, Oxalosuccinate decarboxylase | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | O75874 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1) is a ~46 kDa protein. Catalyzes the NADP(+)-dependent oxidative decarboxylation of isocitrate (D-threo-isocitrate) to 2-ketoglutarate (2-oxoglutarate), which is required by other enzymes such as the phytanoyl-CoA dioxygenase. Plays a critical role in the generation of NADPH, an important cofactor in many biosynthesis pathways. May act as a corneal epithelial crystallin and may be involved in maintaining corneal epithelial transparency. 1. Geisbrecht, BV. et al. (1999) The Journal of biological chemistry 274, 30527-33. PMID: 10521434 2. Dang, L. et al. (2009) Nature 462, 739-44. PMID: 19935646 | ||||||||
| Note | For research use only. |

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