

| 货号 | HP125013 | ||||
|---|---|---|---|---|---|
| 品牌 | abinScience | ||||
| 种属反应性 | Human | ||||
| 应用 | ELISA, IF, IP | ||||
| 同种型 | IgG2a | ||||
| 克隆号 | SAA0196 | ||||
| 靶标 | CECR2, Cat eye syndrome critical region protein 2, KIAA1740 | ||||
| 内毒素水平 | Please contact with the lab for this information. | ||||
| 纯度 | >95% as determined by SDS-PAGE. | ||||
| 纯化方式 | Protein A/G purified from cell culture supernatant. | ||||
| Accession号 | Q9BXF3 | ||||
| RRID | Anti-Human CECR2 IP Antibody (SAA0196) (abinScience Cat# HP125013, RRID:AB_3729730) | ||||
| 状态 | Liquid | ||||
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Chromatin remodeling regulator CECR2 is a ~164 kDa protein. Regulatory subunit of the ATP-dependent CERF-1 and CERF-5 ISWI chromatin remodeling complexes, which form ordered nucleosome arrays on chromatin and facilitate access to DNA during DNA-templated processes such as DNA replication, transcription, and repair. The complexes do not have the ability to slide mononucleosomes to the center of a DNA template. The CERF-1 ISWI chromatin remodeling complex has a lower ATP hydrolysis rate than the CERF-5 ISWI chromatin remodeling complex. Plays a role in various processes during development: required during embryogenesis for neural tube closure and inner ear development. In adults, required for spermatogenesis, via the formation of ISWI-type chromatin complexes. 1. Banting, GS. et al. (2005) Human molecular genetics 14, 513-24. PMID: 15640247 2. Filippakopoulos, P. et al. (2012) Cell 149, 214-31. PMID: 22464331 3. Flynn, EM. et al. (2015) Structure (London, England : 1993) 23, 1801-1814. PMID: 26365797 4. Oppikofer, M. et al. (2017) EMBO reports 18, 1697-1706. PMID: 28801535 5. Liu, L. et al. (2002) Genomics 79, 124-36. PMID: 11827465 | ||||
| Note | For research use only. | ||||
| Isotype Control | Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023) |

SDS-PAGE for Anti-Human CECR2 IP Antibody (SAA0196).



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