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Anti-Human CECR2 IP Recombinant Antibody (SAA0196) (HP125013)

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规格:
  • 50ug
  • 100ug
  • 1mg
数量:
  • 概述

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  • 参考文献

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概述
货号HP125013
品牌abinScience
种属反应性Human
应用ELISA, IF, IP
宿主Mouse
克隆类型Monoclonal
同种型IgG2a, kappa
克隆号SAA0196
靶标CECR2, Cat eye syndrome critical region protein 2, KIAA1740
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号Q9BXF3
RRIDAnti-Human CECR2 IP Antibody (SAA0196) (abinScience Cat# HP125013, RRID:AB_3729730)
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:2000-1:20000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Chromatin remodeling regulator CECR2 is a ~164 kDa protein. Regulatory subunit of the ATP-dependent CERF-1 and CERF-5 ISWI chromatin remodeling complexes, which form ordered nucleosome arrays on chromatin and facilitate access to DNA during DNA-templated processes such as DNA replication, transcription, and repair. The complexes do not have the ability to slide mononucleosomes to the center of a DNA template. The CERF-1 ISWI chromatin remodeling complex has a lower ATP hydrolysis rate than the CERF-5 ISWI chromatin remodeling complex. Plays a role in various processes during development: required during embryogenesis for neural tube closure and inner ear development. In adults, required for spermatogenesis, via the formation of ISWI-type chromatin complexes.

1. Banting, GS. et al. (2005) Human molecular genetics 14, 513-24. PMID: 15640247
2. Filippakopoulos, P. et al. (2012) Cell 149, 214-31. PMID: 22464331
3. Flynn, EM. et al. (2015) Structure (London, England : 1993) 23, 1801-1814. PMID: 26365797
4. Oppikofer, M. et al. (2017) EMBO reports 18, 1697-1706. PMID: 28801535
5. Liu, L. et al. (2002) Genomics 79, 124-36. PMID: 11827465
NoteFor research use only.
Isotype ControlMouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023)
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Human CECR2 IP Antibody (SAA0196).

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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