Anti-Human SETD7 IP Recombinant Antibody (SAA0223) (HP870013)

价格:

规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HP870013

abinScience

种属反应性

Human

ELISA, IF, IP

Mouse

Monoclonal

IgG2a

SAA0223

Lysine N-methyltransferase 7, SET9, SET7/9, Histone H3-K4 methyltransferase SETD7, SET7, SET domain-containing protein 7, SETD7, H3-K4-HMTase SETD7, KIAA1717, Histone-lysine N-methyltransferase SETD7, KMT7

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

Q8WTS6

Anti-Human SETD7 IP Antibody (SAA0223) (abinScience Cat# HP870013, RRID:AB_3729757)

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Histone-lysine N-methyltransferase SETD7 is a ~40 kDa protein. Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Also has methyltransferase activity toward non-histone proteins such as CGAS, p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins.

1. Wang, H. et al. (2001) Molecular cell 8, 1207-17. PMID: 11779497

2. Nishioka, K. et al. (2002) Genes & development 16, 479-89. PMID: 11850410

3. Xiao, B. et al. (2003) Nature 421, 652-6. PMID: 12540855

4. Martens, JH. et al. (2003) Molecular and cellular biology 23, 1808-16. PMID: 12588998

5. Francis, J. et al. (2005) The Journal of biological chemistry 280, 36244-53. PMID: 16141209

9. Xiao, Y. et al. (2022) Bone research 10, 19. PMID: 35210392

For research use only.

Isotype Control

Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173) (MF533507)
Mouse IgG2a Recombinant Isotype Control Antibody (S43.10) (MF533307)

SDS-PAGE

SDS-PAGE for Anti-Human SETD7 IP Antibody (SAA0223).

产品说明书

Anti-Human SETD7 IP Recombinant Antibody (SAA0223).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human SETD7 IP Recombinant Antibody (SAA0223) (HP870013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human SETD7 IP Recombinant Antibody (SAA0223) (HP870013)

概述

图片

参考文献

产品说明书

相关产品推荐

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