注册
CN
首页 > 产品中心 > 抗体 > 一抗

Anti-HMGCR Polyclonal Antibody (PTX19505)

价格:
规格：
数量：
联系我们
一键复制产品信息

  • 概述

  • 图片

  • 参考文献

概述
货号PTX19505
品牌ProteoGenix
描述
Anti-HMGCR Polyclonal Antibody (PTX19505) is a rabbit polyclonal antibody detecting 3-hydroxy-3-methylglutaryl-coenzyme A reductase,HMGCR,HMG-CoA reductase in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human HMGCR (Glu441-Asn875).
靶标3-hydroxy-3-methylglutaryl-coenzyme A reductase,HMGCR,HMG-CoA reductase
纯化方式Purified by antigen affinity column.
Accession号P04035
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) is a ~97 kDa protein. Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol homeostasis. HMGCR is the main target of statins, a class of cholesterol-lowering drugs.

1. Cuccioloni, M. et al. (2011) Journal of lipid research 52, 897-907. PMID: 21357570
2. Luskey, KL. et al. (1985) The Journal of biological chemistry 260, 10271-7. PMID: 2991281
3. Yogev, Y. et al. (2023) Proceedings of the National Academy of Sciences of the United States of America 120, e2217831120. PMID: 36745799
4. Brown, MS. et al. (1980) Journal of lipid research 21, 505-17. PMID: 6995544
5. Istvan, ES. et al. (2001) Science (New York, N.Y.) 292, 1160-4. PMID: 11349148
6. Sarver, RW. et al. (2008) Journal of medicinal chemistry 51, 3804-13. PMID: 18540668
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

相关产品推荐

获取报价

Anti-HMGCR Polyclonal Antibody

  • 7X24小时产品咨询热线：027--87433958(9:00-18:00)，或扫描下方产品专员二维码或在线留言

  • 武汉东湖新技术开发区神墩四路666号研发楼B区3层东

  • 24小时产品查询

    24小时产品查询

  • 24小时产品查询

    扫一扫关注我们

  • 24小时产品查询

    专属渠道经理

Copyright © 2026 武汉艾必赛生物科技有限公司版权所有 所有产品仅可用于工业或者科研等非医疗目的。
鄂ICP备2023002448号-2