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Anti-ANXA1 Polyclonal Antibody (PTX18468)

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概述
货号PTX18468
品牌ProteoGenix
描述
Anti-ANXA1 Polyclonal Antibody (PTX18468) is a rabbit polyclonal antibody detecting LPC1,Calpactin-2,Lipocortin I,ANX1,ANXA1,Phospholipase A2 inhibitory protein,Chromobindin-9,Annexin I,Annexin A1,p35,Calpactin II,Annexin-1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human ANXA1 (Met1-Asn346).
靶标LPC1,Calpactin-2,Lipocortin I,ANX1,ANXA1,Phospholipase A2 inhibitory protein,Chromobindin-9,Annexin I,Annexin A1,p35,Calpactin II,Annexin-1
纯化方式Purified by antigen affinity column.
Accession号P04083
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Annexin A1 (ANXA1) is a ~38 kDa protein. Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Contributes to the adaptive immune response by enhancing signaling cascades that are triggered by T-cell activation, regulates differentiation and proliferation of activated T cells. Promotes the differentiation of T cells into Th1 cells and negatively regulates differentiation into Th2 cells.

1. Arcone, R. et al. (1993) European journal of biochemistry 211, 347-55. PMID: 8425544
2. D'Acquisto, F. et al. (2007) Blood 109, 1095-102. PMID: 17008549
3. McArthur, S. et al. (2009) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 23, 4000-10. PMID: 19625660
4. Pepinsky, RB. et al. (1989) The Biochemical journal 263, 97-103. PMID: 2532504
5. Mailliard, WS. et al. (1996) The Journal of biological chemistry 271, 719-25. PMID: 8557678
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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