

| 货号 | HY216014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-ANXA1 Polyclonal Antibody (HY216014) is a rabbit polyclonal antibody detecting ANXA1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Cavia cutleri.
Highlights
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Human ANXA1 (Met1-Asn346). | ||||||||
| 靶标 | LPC1, Calpactin-2, Lipocortin I, ANX1, ANXA1, Phospholipase A2 inhibitory protein, Chromobindin-9, Annexin I, Annexin A1, p35, Calpactin II, Annexin-1 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P04083 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Annexin A1 (ANXA1) is a ~38 kDa protein. Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Contributes to the adaptive immune response by enhancing signaling cascades that are triggered by T-cell activation, regulates differentiation and proliferation of activated T cells. Promotes the differentiation of T cells into Th1 cells and negatively regulates differentiation into Th2 cells. 1. Arcone, R. et al. (1993) European journal of biochemistry 211, 347-55. PMID: 8425544 2. D'Acquisto, F. et al. (2007) Blood 109, 1095-102. PMID: 17008549 3. McArthur, S. et al. (2009) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 23, 4000-10. PMID: 19625660 4. Pepinsky, RB. et al. (1989) The Biochemical journal 263, 97-103. PMID: 2532504 5. Mailliard, WS. et al. (1996) The Journal of biological chemistry 271, 719-25. PMID: 8557678 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-ANXA1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Hela cell lysate
Lane 2: A431 cell lysate
Lane 3: K562 cell lysate
Lane 4: Jurkat cell lysate



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