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Anti-BRAF Polyclonal Antibody (PTX18487)

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概述
货号PTX18487
品牌ProteoGenix
描述
Anti-BRAF Polyclonal Antibody (PTX18487) is a rabbit polyclonal antibody detecting BRAF1,RAFB1,Proto-oncogene B-Raf,BRAF,v-Raf murine sarcoma viral oncogene homolog B1,p94,Serine/threonine-protein kinase B-raf in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human BRAF (Asn500-His766).
靶标BRAF1,RAFB1,Proto-oncogene B-Raf,BRAF,v-Raf murine sarcoma viral oncogene homolog B1,p94,Serine/threonine-protein kinase B-raf
纯化方式Purified by antigen affinity column.
Accession号P15056
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Serine/threonine-protein kinase B-raf (BRAF) is a ~84 kDa protein. Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus (Probable). Phosphorylates MAP2K1, and thereby activates the MAP kinase signal transduction pathway. Phosphorylates PFKFB2. May play a role in the postsynaptic responses of hippocampal neurons.

1. Brennan, DF. et al. (2011) Nature 472, 366-9. PMID: 21441910
2. Lavoie, H. et al. (2018) Nature 554, 549-553. PMID: 29433126
3. McGrail, K. et al. (2022) Nature communications 13, 7113. PMID: 36402789
4. Stephens, RM. et al. (1992) Molecular and cellular biology 12, 3733-42. PMID: 1508179
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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