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Anti-CAPN2 Polyclonal Antibody (PTX19603)

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概述
货号PTX19603
品牌ProteoGenix
描述
Anti-CAPN2 Polyclonal Antibody (PTX19603) is a rabbit polyclonal antibody detecting Calpain M-type,Calcium-activated neutral proteinase 2,CANPL2,Calpain-2 catalytic subunit,CAPN2,Calpain large polypeptide L2,Calpain-2 large subunit,Millimolar-calpain,M-calpain,CANP 2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human CAPN2 (Leu45-Asp514).
靶标Calpain M-type,Calcium-activated neutral proteinase 2,CANPL2,Calpain-2 catalytic subunit,CAPN2,Calpain large polypeptide L2,Calpain-2 large subunit,Millimolar-calpain,M-calpain,CANP 2
纯化方式Purified by antigen affinity column.
Accession号P17655
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Calpain-2 catalytic subunit (CAPN2) is a ~79 kDa protein. Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226'. Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs.

1. Sánchez-Sánchez, F. et al. (2007) The Journal of biological chemistry 282, 27810-24. PMID: 17650508
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-CAPN2 Polyclonal Antibody

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