Anti-CAPN2 Polyclonal Antibody (HB291014)

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50ug
100ug

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概述
图片
参考文献
产品说明书

概述

货号

HB291014

品牌

abinScience

描述

Anti-CAPN2 Polyclonal Antibody (HB291014) is a rabbit polyclonal antibody detecting CAPN2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Macaca fascicularis.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human CAPN2 (Leu45-Asp514).

靶标

Calpain M-type, Calcium-activated neutral proteinase 2, CANPL2, Calpain-2 catalytic subunit, CAPN2, Calpain large polypeptide L2, Calpain-2 large subunit, Millimolar-calpain, M-calpain, CANP 2

纯化方式

Purified by antigen affinity column.

Accession号

P17655

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Calpain-2 catalytic subunit (CAPN2) is a ~79 kDa protein. Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226'. Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs.

1. Sánchez-Sánchez, F. et al. (2007) The Journal of biological chemistry 282, 27810-24. PMID: 17650508

Note

For research use only.

图片

Western blot

Western blot analysis was performed using anti-CAPN2 polyclonal antibody at 1ug/mL on various samples.
Lane 1: MDA-MB-231 cell lysate
Lane 2: A549 cell lysate
Lane 3: K562 cell lysate
Lane 4: C2C12 cell lysate
Lane 5: PC-3 cell lysate
Lane 6: PC-12 cell lysate
Lane 7: U2OS cell lysate

参考文献

产品说明书

Anti-CAPN2 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-CAPN2 Polyclonal Antibody (HB291014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-CAPN2 Polyclonal Antibody (HB291014)

概述

图片

参考文献

产品说明书

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