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Anti-ACAT1 Polyclonal Antibody (PTX19631)

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概述
货号PTX19631
品牌ProteoGenix
描述
Anti-ACAT1 Polyclonal Antibody (PTX19631) is a rabbit polyclonal antibody detecting ACAT,Acetoacetyl-CoA thiolase,MAT,Acetyl-CoA acetyltransferase,mitochondrial,ACAT1,T2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human ACAT1 (Ala111-Leu427).
靶标ACAT,Acetoacetyl-CoA thiolase,MAT,Acetyl-CoA acetyltransferase,mitochondrial,ACAT1,T2
纯化方式Purified by antigen affinity column.
Accession号P24752
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Acetyl-CoA acetyltransferase, mitochondrial (ACAT1) is a ~45 kDa protein. This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. The activity of the enzyme is reversible and it can also catalyze the condensation of two acetyl-CoA molecules into acetoacetyl-CoA. Thereby, it plays a major role in ketone body metabolism.

1. Fukao, T. et al. (1991) Biochemical and biophysical research communications 179, 124-9. PMID: 1715688
2. Wakazono, A. et al. (1995) Human mutation 5, 34-42. PMID: 7728148
3. Fukao, T. et al. (1998) Human mutation 12, 245-54. PMID: 9744475
4. Haapalainen, AM. et al. (2007) Biochemistry 46, 4305-21. PMID: 17371050
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-ACAT1 Polyclonal Antibody

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