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Anti-DNASE1 Polyclonal Antibody (PTX18557)

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概述
货号PTX18557
品牌ProteoGenix
描述
Anti-DNASE1 Polyclonal Antibody (PTX18557) is a rabbit polyclonal antibody detecting DNL1,Deoxyribonuclease I,DNASE1,Dornase alfa,Deoxyribonuclease-1,DNase I,DRNI in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human DNASE1 (Gly19-Ala259).
靶标DNL1,Deoxyribonuclease I,DNASE1,Dornase alfa,Deoxyribonuclease-1,DNase I,DRNI
纯化方式Purified by antigen affinity column.
Accession号P24855
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Deoxyribonuclease-1 (DNASE1) is a ~31 kDa protein. Serum endocuclease secreted into body fluids by a wide variety of exocrine and endocrine organs. Expressed by non-hematopoietic tissues and preferentially cleaves protein-free DNA. Among other functions, seems to be involved in cell death by apoptosis. Binds specifically to G-actin and blocks actin polymerization. Together with DNASE1L3, plays a key role in degrading neutrophil extracellular traps (NETs).

1. Oliveri, M. et al. (2001) European journal of immunology 31, 743-51. PMID: 11241278
2. Shak, S. et al. (1990) Proceedings of the National Academy of Sciences of the United States of America 87, 9188-92. PMID: 2251263
3. Yasuda, T. et al. (1990) Journal of biochemistry 108, 393-8. PMID: 2277032
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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