Anti-DNASE1 Polyclonal Antibody (HB712014)

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概述
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参考文献
产品说明书

概述

货号

HB712014

品牌

abinScience

描述

Anti-DNASE1 Polyclonal Antibody (HB712014) is a rabbit polyclonal antibody detecting DNASE1 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human DNASE1 (Gly19-Ala259).

靶标

DNL1, Deoxyribonuclease I, DNASE1, Dornase alfa, Deoxyribonuclease-1, DNase I, DRNI

纯化方式

Purified by antigen affinity column.

Accession号

P24855

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Deoxyribonuclease-1 (DNASE1) is a ~31 kDa protein. Serum endocuclease secreted into body fluids by a wide variety of exocrine and endocrine organs. Expressed by non-hematopoietic tissues and preferentially cleaves protein-free DNA. Among other functions, seems to be involved in cell death by apoptosis. Binds specifically to G-actin and blocks actin polymerization. Together with DNASE1L3, plays a key role in degrading neutrophil extracellular traps (NETs).

1. Oliveri, M. et al. (2001) European journal of immunology 31, 743-51. PMID: 11241278

2. Shak, S. et al. (1990) Proceedings of the National Academy of Sciences of the United States of America 87, 9188-92. PMID: 2251263

3. Yasuda, T. et al. (1990) Journal of biochemistry 108, 393-8. PMID: 2277032

Note

For research use only.

图片

参考文献

产品说明书

Anti-DNASE1 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-DNASE1 Polyclonal Antibody (HB712014)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-DNASE1 Polyclonal Antibody (HB712014)

概述

图片

参考文献

产品说明书

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