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Anti-WNT3A Polyclonal Antibody (PTX18704)

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概述
货号PTX18704
品牌ProteoGenix
描述
Anti-WNT3A Polyclonal Antibody (PTX18704) is a rabbit polyclonal antibody detecting Protein Wnt-3a,WNT3A in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human WNT3A (Ser19-Lys352).
靶标Protein Wnt-3a,WNT3A
纯化方式Purified by antigen affinity column.
Accession号P56704
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Protein Wnt-3a (WNT3A) is a ~39 kDa protein. Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family. Required for normal embryonic mesoderm development and formation of caudal somites. Required for normal morphogenesis of the developing neural tube. Mediates self-renewal of the stem cells at the bottom on intestinal crypts (in vitro).

1. Bourhis, E. et al. (2010) The Journal of biological chemistry 285, 9172-9. PMID: 20093360
2. Doubravska, L. et al. (2011) Cellular signalling 23, 837-48. PMID: 21244856
3. MacDonald, BT. et al. (2014) The Journal of biological chemistry 289, 18122-36. PMID: 24841207
4. Mihara, E. et al. (2016) eLife 5. PMID: 26902720
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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