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Anti-WDR5 Polyclonal Antibody (PTX19740)

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概述
货号PTX19740
品牌ProteoGenix
描述
Anti-WDR5 Polyclonal Antibody (PTX19740) is a rabbit polyclonal antibody detecting WDR5,BMP2-induced 3-kb gene protein,WD repeat-containing protein 5,BIG3 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human WDR5 (Met1-Lys120).
靶标WDR5,BMP2-induced 3-kb gene protein,WD repeat-containing protein 5,BIG3
纯化方式Purified by antigen affinity column.
Accession号P61964
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

WD repeat-containing protein 5 (WDR5) is a ~36 kDa protein. Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues.

1. Han, Z. et al. (2006) Molecular cell 22, 137-44. PMID: 16600877
2. Couture, JF. et al. (2006) Nature structural & molecular biology 13, 698-703. PMID: 16829960
3. Guelman, S. et al. (2009) Molecular and cellular biology 29, 1176-88. PMID: 19103755
4. Garapaty, S. et al. (2009) The Journal of biological chemistry 284, 7542-52. PMID: 19131338
5. Patel, A. et al. (2009) The Journal of biological chemistry 284, 24242-56. PMID: 19556245
6. Cai, Y. et al. (2010) The Journal of biological chemistry 285, 4268-72. PMID: 20018852
7. Song, JJ. et al. (2008) The Journal of biological chemistry 283, 35258-64. PMID: 18840606
8. Avdic, V. et al. (2011) Structure (London, England : 1993) 19, 101-8. PMID: 21220120
9. Zhang, P. et al. (2012) Nucleic acids research 40, 4237-46. PMID: 22266653
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-WDR5 Polyclonal Antibody

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