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Anti-CD112/Nectin-2/NECTIN2 Polyclonal Antibody (PTX19817)

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概述
货号PTX19817
品牌ProteoGenix
描述
Anti-CD112/Nectin-2/NECTIN2 Polyclonal Antibody (PTX19817) is a rabbit polyclonal antibody detecting Herpesvirus entry mediator B,Herpes virus entry mediator B,Nectin cell adhesion molecule 2,HVEB,PVRL2,Poliovirus receptor-related protein 2,CD112,PRR2,Nectin-2,HveB,NECTIN2 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human CD112/Nectin-2/NECTIN2 (Gln32-Pro350).
靶标Herpesvirus entry mediator B,Herpes virus entry mediator B,Nectin cell adhesion molecule 2,HVEB,PVRL2,Poliovirus receptor-related protein 2,CD112,PRR2,Nectin-2,HveB,NECTIN2
纯化方式Purified by antigen affinity column.
Accession号Q92692
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Nectin-2 (CD112/PVRL2) is a ~57 kDa protein. Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive.

1. Zhu, Y. et al. (2016) The Journal of experimental medicine 213, 167-76. PMID: 26755705
2. Warner, MS. et al. (1998) Virology 246, 179-89. PMID: 9657005
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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