

| 货号 | PTX20199 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-Human SLC16A2 Polyclonal Antibody (PTX20199) is a rabbit polyclonal antibody detecting Monocarboxylate transporter 7, MCT 8, SLC16A2, MCT 7, MCT8, X-linked PEST-containing transporter, XPCT, Monocarboxylate transporter 8, Solute carrier family 16 member 2 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal |
| 同种型 | IgG |
| 免疫原 | E. coli - derived recombinant Human SLC16A2 (Tyr280-Arg322). |
| 靶标 | Monocarboxylate transporter 7, MCT 8, SLC16A2, MCT 7, MCT8, X-linked PEST-containing transporter, XPCT, Monocarboxylate transporter 8, Solute carrier family 16 member 2 |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | P36021 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Monocarboxylate transporter 8 (SLC16A2) is a ~59 kDa protein. Specific thyroid hormone transmembrane transporter, that mediates both uptake and efflux of thyroid hormones across the cell membrane independently of pH or a Na(+) gradient. Major substrates are the iodothyronines T3 and T4 and to a lesser extent rT3 and 3,3-diiodothyronine (3,3'-T2). Acts as an important mediator of thyroid hormone transport, especially T3, through the blood-brain barrier (Probable). 1. Friesema, EC. et al. (2006) Molecular endocrinology (Baltimore, Md.) 20, 2761-72. PMID: 16887882 2. Friesema, EC. et al. (2008) Molecular endocrinology (Baltimore, Md.) 22, 1357-69. PMID: 18337592 3. Kinne, A. et al. (2010) The Journal of biological chemistry 285, 28054-63. PMID: 20628049 4. Kersseboom, S. et al. (2013) Molecular endocrinology (Baltimore, Md.) 27, 801-13. PMID: 23550058 5. Armour, CM. et al. (2015) PloS one 10, e0139343. PMID: 26426690 6. Novara, F. et al. (2017) Human mutation 38, 260-264. PMID: 27805744 7. Groeneweg, S. et al. (2019) Thyroid : official journal of the American Thyroid Association 29, 1499-1510. PMID: 31436139 8. Vatine, GD. et al. (2017) Cell stem cell 20, 831-843.e5. PMID: 28526555 |
| Note | For research use only. |

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