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Human SLC16A2 Recombinant Protein (N-GST & C-His) (HW839022)

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规格:
  • 50ug
  • 100ug
  • 1mg
数量:
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概述
货号HW839022
品牌abinScience
描述
Recombinant Human SLC16A2 Protein, N-GST & C-His (HW839022) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
  • E. coli Expression — High-yield, cost-effective production.
  • High Purity — >90% as determined by SDS-PAGE.
表达系统E. coli
Accession号P36021
蛋白长度Tyr280-Arg322
应用ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属Homo sapiens (Human)
性质Recombinant
内毒素水平Please contact with the lab for this information.
纯度>90% as determined by SDS-PAGE.
状态Lyophilized
保存溶液 Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

重悬Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名MCT 7, MCT 8, MCT7, MCT8, Monocarboxylate transporter 7, Monocarboxylate transporter 8, SLC16A2, Solute carrier family 16 member 2, X-linked PEST-containing transporter, XPCT
背景

Monocarboxylate transporter 8 is a ~59 kDa protein. Specific thyroid hormone transmembrane transporter, that mediates both uptake and efflux of thyroid hormones across the cell membrane independently of pH or a Na(+) gradient. Major substrates are the iodothyronines T3 and T4 and to a lesser extent rT3 and 3,3-diiodothyronine (3,3'-T2). Acts as an important mediator of thyroid hormone transport, especially T3, through the blood-brain barrier (Probable).

1. Friesema, EC. et al. (2006) Molecular endocrinology (Baltimore, Md.) 20, 2761-72. PMID: 16887882
2. Friesema, EC. et al. (2008) Molecular endocrinology (Baltimore, Md.) 22, 1357-69. PMID: 18337592
3. Kinne, A. et al. (2010) The Journal of biological chemistry 285, 28054-63. PMID: 20628049
4. Kersseboom, S. et al. (2013) Molecular endocrinology (Baltimore, Md.) 27, 801-13. PMID: 23550058
5. Armour, CM. et al. (2015) PloS one 10, e0139343. PMID: 26426690
6. Novara, F. et al. (2017) Human mutation 38, 260-264. PMID: 27805744
7. Groeneweg, S. et al. (2019) Thyroid : official journal of the American Thyroid Association 29, 1499-1510. PMID: 31436139
8. Vatine, GD. et al. (2017) Cell stem cell 20, 831-843.e5. PMID: 28526555
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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