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Anti-Human HTR4 Polyclonal Antibody (PTX20205)

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概述
货号PTX20205
品牌ProteoGenix
描述
Anti-Human HTR4 Polyclonal Antibody (PTX20205) is a rabbit polyclonal antibody detecting 5-hydroxytryptamine receptor 4, 5-HT-4, 5-HT4, Serotonin receptor 4, HTR4 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human HTR4.
靶标5-hydroxytryptamine receptor 4, 5-HT-4, 5-HT4, Serotonin receptor 4, HTR4
纯化方式Purified by antigen affinity column.
Accession号Q13639
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

5-hydroxytryptamine receptor 4 (HTR4) is a ~43 kDa protein. G-protein coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. HTR4 is coupled to G(s) G alpha proteins and mediates activation of adenylate cyclase activity.

1. Mialet, J. et al. (2000) British journal of pharmacology 130, 527-38. PMID: 10821780
2. Kamel, R. et al. (2005) Biochemical pharmacology 70, 1009-18. PMID: 16102731
3. Huang, S. et al. (2022) Molecular cell 82, 2681-2695.e6. PMID: 35714614
4. Blondel, O. et al. (1998) Journal of neurochemistry 70, 2252-61. PMID: 9603189
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-Human HTR4 Polyclonal Antibody

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