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Anti-Human IL19 Polyclonal Antibody (PTX19429)

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概述
货号PTX19429
品牌ProteoGenix
描述
Anti-Human IL19 Polyclonal Antibody (PTX19429) is a rabbit polyclonal antibody detecting Melanoma differentiation-associated protein-like protein, Interleukin-19, IL-19, IL19, NG.1, ZMDA1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human IL19 (Leu25-Ala177).
靶标Melanoma differentiation-associated protein-like protein, Interleukin-19, IL-19, IL19, NG.1, ZMDA1
纯化方式Purified by antigen affinity column.
Accession号Q9UHD0
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Interleukin-19 (IL19) is a ~20 kDa protein. Cytokine that functions as an anti-inflammatory and proangiogenic factor. Polarizes adaptive immunity to an anti-inflammatory phenotype through induction of T-helper 2 responses by both down-regulation of IFN-gamma and up-regulation of IL4 and IL13. Produced by osteocytes, stimulates granulopoiesis and neutrophil formation. Exerts its biological effect through a receptor complex consisting of a heterodimer of IL20RA and IL20RB. In turn, activates the Janus kinase (JAK) and signal transducer and activator of transcription (STAT) pathway, and importantly, STAT3.

1. Small, SH. et al. (2021) Science signaling 14, eaba2611. PMID: 34932373
2. Oral, HB. et al. (2006) European journal of immunology 36, 380-8. PMID: 16365913
3. Parrish-Novak, J. et al. (2002) The Journal of biological chemistry 277, 47517-23. PMID: 12351624
4. Dumoutier, L. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 167, 3545-9. PMID: 11564763
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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