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Anti-Human CA4 Polyclonal Antibody (PTX20307)

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概述
货号PTX20307
品牌ProteoGenix
描述
Anti-Human CA4 Polyclonal Antibody (PTX20307) is a rabbit polyclonal antibody detecting Carbonic anhydrase 4, Carbonate dehydratase IV, CA-IV, CA4, Carbonic anhydrase IV in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human CA4 (Ala19-Lys283).
靶标Carbonic anhydrase 4, Carbonate dehydratase IV, CA-IV, CA4, Carbonic anhydrase IV
纯化方式Purified by antigen affinity column.
Accession号P22748
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Carbonic anhydrase 4 (CA4) is a ~35 kDa protein. Catalyzes the reversible hydration of carbon dioxide into bicarbonate and protons and thus is essential to maintaining intracellular and extracellular pH. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis. It is essential for acid overload removal from the retina and retina epithelium, and acid release in the choriocapillaris in the choroid.

1. Yang, Z. et al. (2005) Human molecular genetics 14, 255-65. PMID: 15563508
2. Temperini, C. et al. (2006) Journal of medicinal chemistry 49, 3019-27. PMID: 16686544
3. Temperini, C. et al. (2006) Chemistry (Weinheim an der Bergstrasse, Germany) 12, 7057-66. PMID: 16807956
4. Temperini, C. et al. (2007) Bioorganic & medicinal chemistry letters 17, 628-35. PMID: 17127057
5. Temperini, C. et al. (2007) Bioorganic & medicinal chemistry letters 17, 2210-5. PMID: 17314045
6. Alvarez, BV. et al. (2007) Investigative ophthalmology & visual science 48, 3459-68. PMID: 17652713
7. Köhler, K. et al. (2007) Angewandte Chemie (International ed. in English) 46, 7697-9. PMID: 17705204
8. Di Fiore, A. et al. (2009) Proteins 74, 164-75. PMID: 18618712
9. Crocetti, L. et al. (2009) Bioorganic & medicinal chemistry letters 19, 1371-5. PMID: 19186056
10. Maresca, A. et al. (2009) Journal of the American Chemical Society 131, 3057-62. PMID: 19206230
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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