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Anti-Human SLC26A8 Polyclonal Antibody (PTX20318)

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概述
货号PTX20318
品牌ProteoGenix
描述
Anti-Human SLC26A8 Polyclonal Antibody (PTX20318) is a rabbit polyclonal antibody detecting Solute carrier family 26 member 8, SLC26A8, Testis anion transporter 1, TAT1, Anion exchange transporter in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human SLC26A8 (Thr664-Val970).
靶标Solute carrier family 26 member 8, SLC26A8, Testis anion transporter 1, TAT1, Anion exchange transporter
纯化方式Purified by antigen affinity column.
Accession号Q96RN1
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Testis anion transporter 1 (SLC26A8) is a ~109 kDa protein. Antiporter that mediates the exchange of sulfate and oxalate against chloride ions across a membrane. Stimulates anion transport activity of CFTR. May cooperate with CFTR in the regulation of chloride and bicarbonate ions fluxes required for activation of the ADCY10/PKA pathway during sperm motility and sperm capacitation. May play a role in sperm tail differentiation and motility and hence male fertility.

1. Toure, A. et al. (2001) The Journal of biological chemistry 276, 20309-15. PMID: 11278976
2. Lohi, H. et al. (2002) The Journal of biological chemistry 277, 14246-54. PMID: 11834742
3. Rode, B. et al. (2012) Human molecular genetics 21, 1287-98. PMID: 22121115
4. Dirami, T. et al. (2013) American journal of human genetics 92, 760-6. PMID: 23582645
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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