注册
CN
首页 > 产品中心 > 抗体 > 一抗

Anti-ALOX15B Polyclonal Antibody (PTX20468)

价格:
规格：
数量：
联系我们
一键复制产品信息

  • 概述

  • 图片

  • 参考文献

概述
货号PTX20468
品牌ProteoGenix
描述
Anti-ALOX15B Polyclonal Antibody (PTX20468) is a rabbit polyclonal antibody detecting 15-lipoxygenase 2, 15-LOX-B, 15-LOX-2, Linoleate 13-lipoxygenase 15-LOb, Arachidonate 15-lipoxygenase B, Polyunsaturated fatty acid lipoxygenase ALOX15B, ALOX15B, Arachidonate 15-lipoxygenase type II in ELISA, IHC, WB. Suitable for Human, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Rat
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human ALOX15B (Ala2-Gly121).
靶标15-lipoxygenase 2, 15-LOX-B, 15-LOX-2, Linoleate 13-lipoxygenase 15-LOb, Arachidonate 15-lipoxygenase B, Polyunsaturated fatty acid lipoxygenase ALOX15B, ALOX15B, Arachidonate 15-lipoxygenase type II
纯化方式Purified by antigen affinity column.
Accession号O15296
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Polyunsaturated fatty acid lipoxygenase ALOX15B is a ~75 kDa protein. Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids (PUFAs) generating a spectrum of bioactive lipid mediators (Probable). It inserts peroxyl groups at C15 of arachidonate ((5Z,8Z,11Z,14Z)-eicosatetraenoate) producing (15S)-hydroperoxyeicosatetraenoate/(15S)-HPETE (Probable). Also peroxidizes linoleate ((9Z,12Z)-octadecadienoate) to 13-hydroperoxyoctadecadienoate/13-HPODE (Probable). Oxygenates arachidonyl derivatives such as 2-arachidonoylglycerol (2-AG) leading to the production and extracellular release of 15-hydroxyeicosatetraenoyl glycerol (15-HETE-G) that acts as a peroxisome proliferator-activated receptor alpha agonist. Has the ability to efficiently class-switch ALOX5 pro-inflammatory mediators into anti-inflammatory intermediates.

1. Kilty, I. et al. (1999) European journal of biochemistry 266, 83-93. PMID: 10542053
2. Jisaka, M. et al. (2000) The Journal of biological chemistry 275, 1287-93. PMID: 10625675
3. Bhatia, B. et al. (2003) The Journal of biological chemistry 278, 25091-100. PMID: 12704195
4. Prusakiewicz, JJ. et al. (2007) Archives of biochemistry and biophysics 464, 260-8. PMID: 17493578
5. Turman, MV. et al. (2008) Biochemistry 47, 3917-25. PMID: 18311922
6. Horn, T. et al. (2013) Redox biology 1, 566-77. PMID: 24282679
7. Kobe, MJ. et al. (2014) The Journal of biological chemistry 289, 8562-9. PMID: 24497644
8. Perry, SC. et al. (2020) Journal of lipid research 61, 1087-1103. PMID: 32404334
9. Brash, AR. et al. (1997) Proceedings of the National Academy of Sciences of the United States of America 94, 6148-52. PMID: 9177185
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

相关产品推荐

获取报价

Anti-ALOX15B Polyclonal Antibody

  • 7X24小时产品咨询热线：027--87433958(9:00-18:00)，或扫描下方产品专员二维码或在线留言

  • 武汉东湖新技术开发区神墩四路666号研发楼B区3层东

  • 24小时产品查询

    24小时产品查询

  • 24小时产品查询

    扫一扫关注我们

  • 24小时产品查询

    专属渠道经理

Copyright © 2026 武汉艾必赛生物科技有限公司版权所有 所有产品仅可用于工业或者科研等非医疗目的。
鄂ICP备2023002448号-2