首页 > 产品中心 > 抗体 > 一抗

Anti-Mouse SPHK2 Polyclonal Antibody (PTX20028)

概述
图片
参考文献

概述

货号	PTX20028
品牌	ProteoGenix
描述	Anti-Mouse SPHK2 Polyclonal Antibody (PTX20028) is a rabbit polyclonal antibody detecting SK2, Sphingosine kinase 2, SPHK2, SK 2, SPK 2 in ELISA, IHC, WB. Suitable for Mouse. Highlights Affinity Purified — Minimal background and high purity for reliable results. Multi-Application — Validated across multiple applications.
种属反应性	Mouse
应用	ELISA, IHC, WB
宿主	Rabbit
克隆类型	Polyclonal
同种型	IgG
免疫原	E. coli - derived recombinant Mouse SPHK2 (Ile15-Gly276).
靶标	SK2, Sphingosine kinase 2, SPHK2, SK 2, SPK 2
纯化方式	Purified by antigen affinity column.
Accession号	Q9JIA7
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	Sphingosine kinase 2 (SPHK2) is a ~65 kDa protein. Catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on D-erythro-dihydrosphingosine, D-erythro-sphingosine and L-threo-dihydrosphingosine. Binds phosphoinositides. In contrast to prosurvival SPHK1, has a positive effect on intracellular ceramide levels, inhibits cells growth and enhances apoptosis. In mitochondria, is important for cytochrome-c oxidase assembly and mitochondrial respiration. 1. Maceyka, M. et al. (2005) The Journal of biological chemistry 280, 37118-29. PMID: 16118219 2. Olivera, A. et al. (2007) Immunity 26, 287-97. PMID: 17346996 3. Hisano, Y. et al. (2011) The Journal of biological chemistry 286, 1758-66. PMID: 21084291 4. Liu, H. et al. (2000) The Journal of biological chemistry 275, 19513-20. PMID: 10751414 5. Strub, GM. et al. (2011) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 25, 600-12. PMID: 20959514 6. Sivasubramanian, M. et al. (2015) Neuroscience 290, 636-48. PMID: 25637806 7. Ravichandran, S. et al. (2019) Biochimica et biophysica acta. Molecular basis of disease 1865, 570-576. PMID: 30593892
Note	For research use only.

图片

参考文献

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

=

浓度

×

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

×

V₁ (起始体积)

=

工作液

C₂ (终浓度)

×

V₂ (终体积)

相关产品推荐

Anti-Mouse SPHK2 Polyclonal Antibody

7X24小时产品咨询热线：027--87433958(9:00-18:00)，或扫描下方产品专员二维码或在线留言
武汉东湖新技术开发区神墩四路666号研发楼B区3层东

24小时产品查询
扫一扫关注我们
专属渠道经理

Copyright © 2026 武汉艾必赛生物科技有限公司版权所有所有产品仅可用于工业或者科研等非医疗目的。

鄂ICP备2023002448号-2