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Anti-Mouse IL4 Antibody (11B11) (PTX19192)

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概述
货号PTX19192
品牌ProteoGenix
描述
Anti-Mouse IL4 Antibody (11B11) [11B11] (PTX19192) is a rat monoclonal antibody detecting Binetrakin, B-cell stimulatory factor 1, Pitrakinra, Lymphocyte stimulatory factor 1, IL-4, BSF-1, IL4, Interleukin-4 in Blocking, ELISA, FCM. Suitable for Mouse.
Highlights
  • Protein A/G purified from cell culture supernatant. — Ensuring high specificity and minimal background.
  • Multi-Application — Validated across multiple applications.
种属反应性Mouse
应用Blocking, ELISA, FCM
宿主Rat
同种型IgG1, kappa
克隆号11B11
克隆类型Monoclonal
靶标Binetrakin, B-cell stimulatory factor 1, Pitrakinra, Lymphocyte stimulatory factor 1, IL-4, BSF-1, IL4, Interleukin-4
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P07750
状态Liquid
保存溶液 0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Interleukin-4 (IL4) is a ~15 kDa protein. Cytokine secreted primarily by mast cells, T-cells, eosinophils, and basophils that plays a role in regulating antibody production, hematopoiesis and inflammation, and the development of effector T-cell responses. Induces the expression of class II MHC molecules on resting B-cells. Enhances both secretion and cell surface expression of IgE and IgG1. Also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages.

1. Lee, F. et al. (1986) Proceedings of the National Academy of Sciences of the United States of America 83, 2061-5. PMID: 3083412
2. Sideras, P. et al. (1987) Advances in experimental medicine and biology 213, 227-36. PMID: 3498301
3. Terawaki, S. et al. (2015) The Journal of cell biology 210, 1133-52. PMID: 26416964
4. Moon, ML. et al. (2015) Behavior genetics 45, 451-60. PMID: 25772794
5. Bogale, TMH. et al. (2017) Journal of immunology (Baltimore, Md. : 1950) 198, 2681-2688. PMID: 28202615
6. Edukulla, R. et al. (2015) The Journal of biological chemistry 290, 13510-20. PMID: 25847241
7. Kaplan, MH. et al. (1996) Immunity 4, 313-9. PMID: 8624821
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-Mouse IL4 Antibody (11B11)

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