

| 货号 | HY086034 | ||||||
|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||
| 描述 |
Anti-Tau (phosphe T217) Polyclonal Antibody (HY086034) is a rabbit polyclonal antibody detecting tau in WB, ELISA. Suitable for Human.
Highlights
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| 种属反应性 | Human | ||||||
| 应用 | WB, ELISA | ||||||
| 宿主 | Rabbit | ||||||
| 同种型 | IgG | ||||||
| 克隆类型 | Polyclonal | ||||||
| 靶标 | tau | ||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||
| 纯度 | >90% as determined by SDS-PAGE. | ||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||
| Accession号 | P10636 | ||||||
| 状态 | Liquid | ||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 重悬 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. | ||||||
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. | ||||||
| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||
| 别名 | Microtubule-associated protein tau, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau, MAPT | ||||||
| 背景 | Microtubule-associated protein tau is a ~78 kDa protein. Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. 1. Yoshida, H. et al. (2012) Journal of neurochemistry 120, 165-76. PMID: 21985311 2. Sandberg, A. et al. (2020) Neurobiology of disease 146, 105079. PMID: 32961270 | ||||||
| Note | For research use only. |

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