

| 货号 | HA025033 | ||||
|---|---|---|---|---|---|
| 品牌 | abinScience | ||||
| 种属反应性 | Human | ||||
| 应用 | ELISA, FCM | ||||
| 同种型 | IgG4, kappa | ||||
| 克隆号 | REGN7999 | ||||
| 靶标 | Transmembrane protease serine 6, EC:3.4.21.-, Matriptase-2, TMPRSS6 | ||||
| 内毒素水平 | Please contact with the lab for this information. | ||||
| 纯度 | >95% as determined by SDS-PAGE. | ||||
| 纯化方式 | Protein A/G purified from cell culture supernatant. | ||||
| Accession号 | Q8IU80 | ||||
| 状态 | Liquid | ||||
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 背景 | Transmembrane protease serine 6 (TMPRSS6) is a ~90 kDa protein. Membrane-bound serine protease. Through the cleavage of cell surface hemojuvelin (HJV), a regulator of the expression of the iron absorption-regulating hormone hepicidin/HAMP, plays a role in iron homeostasis. 1. Silvestri, L. et al. (2008) Cell metabolism 8, 502-11. PMID: 18976966 2. Stirnberg, M. et al. (2010) The Biochemical journal 430, 87-95. PMID: 20518742 3. De Falco, L. et al. (2014) Human mutation 35, 1321-9. PMID: 25156943 4. McDonald, CJ. et al. (2015) American journal of physiology. Cell physiology 308, C539-47. PMID: 25588876 5. Finberg, KE. et al. (2008) Nature genetics 40, 569-71. PMID: 18408718 | ||||
| Note | For research use only |

SDS-PAGE for Anti-Human TMPRSS6 Antibody (REGN7999)



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