

| 货号 | HA025016 |
|---|---|
| 品牌 | abinScience |
| 描述 |
exerenibart (HA025016) is a research-grade recombinant antibody targeting TMPRSS6.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 宿主 | Human |
| 同种型 | IgG4, Kappa |
| 种属 | Human |
| 克隆类型 | Monoclonal |
| 靶标 | TMPRSS6 |
| 内毒素水平 | < 10 EU/mg |
| 纯度 | >95% as determined by SDS-PAGE. |
| Accession号 | Q8IU80 |
| 状态 | Liquid |
| 重悬 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | 2996101-49-4 |
| 背景 | Transmembrane protease serine 6 (TMPRSS6) is a ~90 kDa protein. Membrane-bound serine protease. Through the cleavage of cell surface hemojuvelin (HJV), a regulator of the expression of the iron absorption-regulating hormone hepicidin/HAMP, plays a role in iron homeostasis. 1. Silvestri, L. et al. (2008) Cell metabolism 8, 502-11. PMID: 18976966 2. Stirnberg, M. et al. (2010) The Biochemical journal 430, 87-95. PMID: 20518742 3. De Falco, L. et al. (2014) Human mutation 35, 1321-9. PMID: 25156943 4. McDonald, CJ. et al. (2015) American journal of physiology. Cell physiology 308, C539-47. PMID: 25588876 5. Finberg, KE. et al. (2008) Nature genetics 40, 569-71. PMID: 18408718 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for Research Grade exerenibart



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