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Anti-Human Matriptase 2 Reference Antibody (Exerenibart, RUO) (HA025016)

价格:
规格:
  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
数量:
  • 概述

  • 图片

  • 参考文献

  • 产品说明书

概述
货号HA025016
品牌abinScience
描述
exerenibart (HA025016) is a research-grade recombinant antibody targeting TMPRSS6.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
种属反应性Human
应用ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主Human
同种型IgG4, Kappa
种属Human
克隆类型Monoclonal
靶标TMPRSS6
内毒素水平< 10 EU/mg
纯度>95% as determined by SDS-PAGE.
Accession号Q8IU80
状态Liquid
重悬Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名2996101-49-4
背景

Transmembrane protease serine 6 (TMPRSS6) is a ~90 kDa protein. Membrane-bound serine protease. Through the cleavage of cell surface hemojuvelin (HJV), a regulator of the expression of the iron absorption-regulating hormone hepicidin/HAMP, plays a role in iron homeostasis.

1. Silvestri, L. et al. (2008) Cell metabolism 8, 502-11. PMID: 18976966
2. Stirnberg, M. et al. (2010) The Biochemical journal 430, 87-95. PMID: 20518742
3. De Falco, L. et al. (2014) Human mutation 35, 1321-9. PMID: 25156943
4. McDonald, CJ. et al. (2015) American journal of physiology. Cell physiology 308, C539-47. PMID: 25588876
5. Finberg, KE. et al. (2008) Nature genetics 40, 569-71. PMID: 18408718
NoteFor research use only. Not suitable for clinical or therapeutic use.
图片
  • SDS-PAGE

    SDS-PAGE for Research Grade exerenibart

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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