Anti-Human EMP2 Polyclonal Antibody (HX012014)

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概述
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参考文献
产品说明书

概述

货号

HX012014

品牌

abinScience

描述

Anti-Human EMP2 Polyclonal Antibody (HX012014) is a rabbit polyclonal antibody detecting Epithelial membrane protein 2; EMP-2; Protein XMP; EMP2; XMP in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant human EMP2 (Ile21-Thr67).

靶标

Epithelial membrane protein 2; EMP-2; Protein XMP; EMP2; XMP

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

P54851

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Epithelial membrane protein 2 (EMP2) is a ~19 kDa protein. Functions as a key regulator of cell membrane composition by regulating protein surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion. Regulates transepithelial migration of neutrophils into the alveolar lumen, potentially via mediation of cell surface expression of adhesion markers and lipid raft formation. Negatively regulates caveolae formation by reducing CAV1 expression and CAV1 amount by increasing lysosomal degradation. Facilitates surface trafficking and formation of lipid rafts bearing GPI-anchor proteins.

1. Gee, HY. et al. (2014) American journal of human genetics 94, 884-90. PMID: 24814193

2. Wadehra, M. et al. (2005) Developmental biology 287, 336-45. PMID: 16216233

3. Morales, SA. et al. (2013) Investigative ophthalmology & visual science 54, 2367-72. PMID: 23439602

4. Fu, M. et al. (2011) PloS one 6, e19945. PMID: 21637765

5. Morales, SA. et al. (2012) Experimental eye research 102, 10-6. PMID: 22728127

6. Morales, SA. et al. (2009) Investigative ophthalmology & visual science 50, 4949-56. PMID: 19494199

7. Wilson, HL. et al. (2002) The Journal of biological chemistry 277, 34017-23. PMID: 12107182

8. Gordon, LK. et al. (2013) Oncogene 32, 5369-76. PMID: 23334331

9. Wadehra, M. et al. (2006) Developmental biology 292, 430-41. PMID: 16487956

Note

For research use only

图片

Western blot

Lane 1: Mouse spleen lysate

参考文献

产品说明书

Anti-Human EMP2 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human EMP2 Polyclonal Antibody (HX012014)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human EMP2 Polyclonal Antibody (HX012014)

概述

图片

参考文献

产品说明书

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