Anti-Human EMP2 Reference Antibody (PG-101, RUO) (HX012016)

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概述

货号	HX012016
品牌	abinScience
描述	Anti-Human EMP2 (PG-101) (HX012016) is a research-grade recombinant antibody targeting Epithelial membrane protein 2. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
种属反应性	Human
应用	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主	Human
克隆类型	Monoclonal
同种型	IgG
克隆号	PG-101
表达系统	Mammalian cells
靶标	Epithelial membrane protein 2, EMP2, Protein XMP, XMP, EMP-2
内毒素水平	< 10 EU/mg
纯度	>95% purity as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P54851
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	PG-101, PG101, PG101
背景	Epithelial membrane protein 2 (EMP2) is a ~19 kDa protein. Functions as a key regulator of cell membrane composition by regulating protein surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion. Regulates transepithelial migration of neutrophils into the alveolar lumen, potentially via mediation of cell surface expression of adhesion markers and lipid raft formation. Negatively regulates caveolae formation by reducing CAV1 expression and CAV1 amount by increasing lysosomal degradation. Facilitates surface trafficking and formation of lipid rafts bearing GPI-anchor proteins. 1. Gee, HY. et al. (2014) American journal of human genetics 94, 884-90. PMID: 24814193 2. Wadehra, M. et al. (2005) Developmental biology 287, 336-45. PMID: 16216233 3. Morales, SA. et al. (2013) Investigative ophthalmology & visual science 54, 2367-72. PMID: 23439602 4. Fu, M. et al. (2011) PloS one 6, e19945. PMID: 21637765 5. Morales, SA. et al. (2012) Experimental eye research 102, 10-6. PMID: 22728127 6. Morales, SA. et al. (2009) Investigative ophthalmology & visual science 50, 4949-56. PMID: 19494199 7. Wilson, HL. et al. (2002) The Journal of biological chemistry 277, 34017-23. PMID: 12107182 8. Gordon, LK. et al. (2013) Oncogene 32, 5369-76. PMID: 23334331 9. Wadehra, M. et al. (2006) Developmental biology 292, 430-41. PMID: 16487956
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for Anti-Human EMP2 Reference Antibody (PG-101, RUO)

参考文献

产品说明书

Anti-Human EMP2 Reference Antibody (PG-101, RUO).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

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实验相关试剂

Anti-Human EMP2 Reference Antibody (PG-101, RUO) (HX012016)

概述

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参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human EMP2 Reference Antibody (PG-101, RUO) (HX012016)

概述

图片

参考文献

产品说明书

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