

| 货号 | HC032014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human SLC10A2 Polyclonal Antibody (HC032014) is a rabbit polyclonal antibody detecting ileal; Solute carrier family 10 member 2; SLC10A2; ASBT; ISBT; NTCP2 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human SLC10A2 (Asn2-Asn28&Gly104-Ser126&Arg246-Asn284&Gly306-Lys348). | ||||||||
| 靶标 | Ileal sodium/bile acid cotransporter; Apical sodium-dependent bile acid transporter; ASBT; Ileal Na(+)/bile acid cotransporter; Ileal sodium-dependent bile acid transporter; IBAT; ISBT; Na(+)-dependent ileal bile acid transporter; Sodium/taurocholate cotransporting polypeptide, ileal; Solute carrier family 10 member 2; SLC10A2; ASBT; ISBT; NTCP2 | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q12908 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Ileal sodium/bile acid cotransporter (SLC10A2) is a ~37 kDa protein. Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Transports various bile acids, unconjugated or conjugated, such as cholate and taurocholate. Also responsible for bile acid transport in the renal proximal tubules, a salvage mechanism that helps conserve bile acids (Probable). Works collaboratively with the Na(+)-taurocholate cotransporting polypeptide (NTCP), the organic solute transporter (OST), and the bile salt export pump (BSEP), to ensure efficacious biological recycling of bile acids during enterohepatic circulation. 1. Wong, MH. et al. (1995) The Journal of biological chemistry 270, 27228-34. PMID: 7592981 2. Craddock, AL. et al. (1998) The American journal of physiology 274, G157-69. PMID: 9458785 3. Weinman, SA. et al. (1998) The Journal of biological chemistry 273, 34691-5. PMID: 9856990 4. Kunst, RF. et al. (2021) Hepatology (Baltimore, Md.) 73, 2577-2585. PMID: 33222321 | ||||||||
| Note | For research use only |

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