Anti-Human GLP-1R Reference Antibody (Glutazumab, RUO) (HW328066)

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概述

货号	HW328066
品牌	abinScience
描述	Research Grade Glutazumab (HW328066) is a human monoclonal antibody detecting Glucagon-like peptide 1 receptor in ELISA, Bioactivity: FACS, Functional assay, Research in vivo. Suitable for Human. Highlights ●Multi-Application — Validated across multiple applications.
种属反应性	Human
应用	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主	Human
克隆类型	Monoclonal
同种型	IgG2, kappa
靶标	Glucagon-like peptide 1 receptor, GLP-1 receptor, GLP-1-R, GLP-1R, GLP1R
内毒素水平	< 10 EU/mg
纯度	>95% as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P43220
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	GMA105
背景	Glucagon-like peptide 1 receptor (GLP1R) is a ~53 kDa protein. G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1. 1. Underwood, CR. et al. (2010) The Journal of biological chemistry 285, 723-30. PMID: 19861722 2. Lau, J. et al. (2015) Journal of medicinal chemistry 58, 7370-80. PMID: 26308095 3. Hennen, S. et al. (2016) Scientific reports 6, 26236. PMID: 27196125 4. Song, G. et al. (2017) Nature 546, 312-315. PMID: 28514449 5. van Eyll, B. et al. (1994) FEBS letters 348, 7-13. PMID: 7517895 6. Graziano, MP. et al. (1993) Biochemical and biophysical research communications 196, 141-6. PMID: 8216285 7. Thorens, B. et al. (1993) Diabetes 42, 1678-82. PMID: 8405712
Note	For research use only.
Isotype Control	Human IgG2 Recombinant Isotype Control Antibody (HyHEL-10) (HV988107)

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SDS-PAGE

SDS-PAGE for Anti-Human GLP1R Reference Antibody (Glutazumab, RUO)

参考文献

产品说明书

Anti-Human GLP-1R Reference Antibody (Glutazumab, RUO).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human GLP-1R Reference Antibody (Glutazumab, RUO) (HW328066)

概述

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参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human GLP-1R Reference Antibody (Glutazumab, RUO) (HW328066)

概述

图片

参考文献

产品说明书

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