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Anti-RABV glycoprotein G Reference Antibody (Rafivirumab, RUO) (VK632066)

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概述
货号VK632066
品牌abinScience
描述
Research Grade Rafivirumab (VK632066) is a canis monoclonal antibody detecting Glycoprotein in ELISA, FACS, Functional assay, Research in vivo. Suitable for Rabies virus (RABV).
Highlights
  • ●Multi-Application — Validated across multiple applications.
种属反应性Rabies virus (RABV)
应用ELISA, FACS, Functional assay, Research in vivo
宿主Canine
克隆类型Monoclonal
同种型IgG2a, kappa
经测试应用WB
靶标Glycoprotein, G
内毒素水平< 10 EU/mg
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号O92284
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Glycoprotein (glycoprotein G) is a ~58 kDa protein. Attaches the virus to host cellular receptor, inducing endocytosis of the virion by using different host proteins including TFRC, GRM2 and ITGB1. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells.

NoteFor research use only.
图片

  • SDS-PAGE

    SDS-PAGE for Research Grade Rafivirumab

  • Western blot

    Western blot analysis was performed using anti-/ monoclonal antibody at 1ug/mL on various samples.
    Lane 1: recombinant Rabies virus/RABV G/Glycoprotein(Catalog No: VK632012)
    Lane 2: negative control

参考文献
产品说明书
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-RABV glycoprotein G Reference Antibody (Rafivirumab, RUO)

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