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Anti-HCN4 Recombinant Nanobody (SAA2585) (HY088043)

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规格:
  • 50ug
  • 100ug
  • 1mg
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概述
货号HY088043
品牌abinScience
描述
Anti-HCN4 Nanobody (SAA2585) [SAA2585] (HY088043) is a alpaca monoclonal antibody detecting HCN4 in ELISA. Suitable for Human, Mouse, and Rabbit.
Highlights
  • Multi-Species — Cross-reactive for translational research.
种属反应性Rabbit
应用ELISA
宿主Alpaca
同种型VHH-His
克隆号SAA2585
克隆类型Monoclonal
靶标HCN4, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Purified by Nickel column.
Accession号Q9Y3Q4
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:2000-1:20000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (HCN4) is a ~129 kDa protein. Hyperpolarization-activated ion channel that are permeable to Na(+) and K(+) ions with very slow activation and inactivation. Exhibits higher selectivity for K(+) over Na(+) ions. Contributes to the native pacemaker currents in heart (If) that regulate the rhythm of heart beat (Probable). Contributes to the native pacemaker currents in neurons (Ih) (Probable). May mediate responses to sour stimuli.

1. Ludwig, A. et al. (1999) The EMBO journal 18, 2323-9. PMID: 10228147
2. Seifert, R. et al. (1999) Proceedings of the National Academy of Sciences of the United States of America 96, 9391-6. PMID: 10430953
3. Xu, X. et al. (2010) The Journal of biological chemistry 285, 37082-91. PMID: 20829353
4. Milanesi, R. et al. (2006) The New England journal of medicine 354, 151-7. PMID: 16407510
5. Ueda, K. et al. (2009) Journal of human genetics 54, 115-21. PMID: 19165230
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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