

| 货号 | HY088043 | ||||
|---|---|---|---|---|---|
| 品牌 | abinScience | ||||
| 描述 |
Anti-HCN4 Nanobody (SAA2585) [SAA2585] (HY088043) is a alpaca monoclonal antibody detecting HCN4 in ELISA. Suitable for Human, Mouse, and Rabbit.
Highlights
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| 种属反应性 | Rabbit | ||||
| 应用 | ELISA | ||||
| 宿主 | Alpaca | ||||
| 同种型 | VHH-His | ||||
| 克隆号 | SAA2585 | ||||
| 克隆类型 | Monoclonal | ||||
| 靶标 | HCN4, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | ||||
| 内毒素水平 | Please contact with the lab for this information. | ||||
| 纯度 | >95% as determined by SDS-PAGE. | ||||
| 纯化方式 | Purified by Nickel column. | ||||
| Accession号 | Q9Y3Q4 | ||||
| 状态 | Liquid | ||||
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 背景 | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (HCN4) is a ~129 kDa protein. Hyperpolarization-activated ion channel that are permeable to Na(+) and K(+) ions with very slow activation and inactivation. Exhibits higher selectivity for K(+) over Na(+) ions. Contributes to the native pacemaker currents in heart (If) that regulate the rhythm of heart beat (Probable). Contributes to the native pacemaker currents in neurons (Ih) (Probable). May mediate responses to sour stimuli. 1. Ludwig, A. et al. (1999) The EMBO journal 18, 2323-9. PMID: 10228147 2. Seifert, R. et al. (1999) Proceedings of the National Academy of Sciences of the United States of America 96, 9391-6. PMID: 10430953 3. Xu, X. et al. (2010) The Journal of biological chemistry 285, 37082-91. PMID: 20829353 4. Milanesi, R. et al. (2006) The New England journal of medicine 354, 151-7. PMID: 16407510 5. Ueda, K. et al. (2009) Journal of human genetics 54, 115-21. PMID: 19165230 | ||||
| Note | For research use only |

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