



| 货号 | HY088013 | ||||
|---|---|---|---|---|---|
| 品牌 | abinScience | ||||
| 种属反应性 | Human | ||||
| 应用 | IF, IHC, WB | ||||
| 同种型 | IgG1 | ||||
| 克隆号 | N114/10.1 | ||||
| 靶标 | HCN4, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | ||||
| 内毒素水平 | Please contact with the lab for this information. | ||||
| 纯度 | >95% as determined by SDS-PAGE. | ||||
| 纯化方式 | Protein A/G purified from cell culture supernatant. | ||||
| Accession号 | Q9Y3Q4 | ||||
| 状态 | Liquid | ||||
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
||||
| 产品使用信息 |
| ||||
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (HCN4) is a ~129 kDa protein. Hyperpolarization-activated ion channel that are permeable to Na(+) and K(+) ions with very slow activation and inactivation. Exhibits higher selectivity for K(+) over Na(+) ions. Contributes to the native pacemaker currents in heart (If) that regulate the rhythm of heart beat (Probable). Contributes to the native pacemaker currents in neurons (Ih) (Probable). May mediate responses to sour stimuli. 1. Ludwig, A. et al. (1999) The EMBO journal 18, 2323-9. PMID: 10228147 2. Seifert, R. et al. (1999) Proceedings of the National Academy of Sciences of the United States of America 96, 9391-6. PMID: 10430953 3. Xu, X. et al. (2010) The Journal of biological chemistry 285, 37082-91. PMID: 20829353 4. Milanesi, R. et al. (2006) The New England journal of medicine 354, 151-7. PMID: 16407510 5. Ueda, K. et al. (2009) Journal of human genetics 54, 115-21. PMID: 19165230 | ||||
| Note | For research use only. | ||||
| Isotype Control | Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21) (MV080207) |

SEC-HPLC detection for Anti-Human HCN4 Antibody (N114/10.1).

SDS-PAGE for Anti-Human HCN4 Antibody (N114/10.1).





24小时产品查询

扫一扫关注我们

专属渠道经理