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Anti-Human MB Monoclonal Antibody (1A601) (HF785065)

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概述
货号HF785065
品牌abinScience
描述
Anti-Human MB Monoclonal Antibody (1A601) [1A601] (HF785065) is a mouse monoclonal antibody detecting Human MB in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Recombinant — Superior batch-to-batch reproducibility with defined sequences.
  • ●Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Mouse
克隆类型Monoclonal
同种型IgG
克隆号1A601
免疫原E. coli - derived recombinant human MB (Met1-Gly154).
靶标Myoglobin, Nitrite reductase MB, EC:1.7.-.-, Pseudoperoxidase MB, EC:1.11.1.-, MB
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P02144
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Myoglobin (MB) is a ~17 kDa protein. Monomeric heme protein which primary function is to store oxygen and facilitate its diffusion within muscle tissues. Reversibly binds oxygen through a pentacoordinated heme iron and enables its timely and efficient release as needed during periods of heightened demand. Depending on the oxidative conditions of tissues and cells, and in addition to its ability to bind oxygen, it also has a nitrite reductase activity whereby it regulates the production of bioactive nitric oxide. Under stress conditions, like hypoxia and anoxia, it also protects cells against reactive oxygen species thanks to its pseudoperoxidase activity.

1. Olivé, M. et al. (2019) Nature communications 10, 1396. PMID: 30918256
2. Hofbauer, S. et al. (2022) The FEBS journal 289, 1105-1117. PMID: 34679218
3. Quesnelle, K. et al. (2020) Nitric oxide : biology and chemistry 104-105, 36-43. PMID: 32891753
NoteFor research use only.
图片

  • SDS-PAGE

    SDS-PAGE for Anti-Human MB Monoclonal Antibody (1A601)

参考文献
产品说明书
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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