Anti-LGALS8 Polyclonal Antibody (HT448014)

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概述
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参考文献
产品说明书

概述

货号

HT448014

品牌

abinScience

描述

Anti-LGALS8 Polyclonal Antibody (HT448014) is a rabbit polyclonal antibody detecting LGALS8 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human LGALS8 (Met2-Trp317).

靶标

PCTA-1, Po66 carbohydrate-binding protein, Po66-CBP, Galectin-8, Gal-8, LGALS8, Prostate carcinoma tumor antigen 1

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

O00214

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Galectin-8 (GAL-8) is a ~35 kDa protein. Beta-galactoside-binding lectin that acts as a sensor of membrane damage caused by infection and restricts the proliferation of infecting pathogens by targeting them for autophagy. Detects membrane rupture by binding beta-galactoside ligands located on the lumenal side of the endosome membrane; these ligands becoming exposed to the cytoplasm following rupture. Restricts infection by initiating autophagy via interaction with CALCOCO2/NDP52. Required to restrict infection of bacterial invasion such as S.typhimurium. Also required to restrict infection of Picornaviridae viruses.

1. Thurston, TL. et al. (2012) Nature 482, 414-8. PMID: 22246324

2. Staring, J. et al. (2017) Nature 541, 412-416. PMID: 28077878

3. Ideo, H. et al. (2011) The Journal of biological chemistry 286, 11346-55. PMID: 21288902

Note

For research use only.

图片

参考文献

产品说明书

Anti-LGALS8 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-LGALS8 Polyclonal Antibody (HT448014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-LGALS8 Polyclonal Antibody (HT448014)

概述

图片

参考文献

产品说明书

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