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Anti-LGALS8 Polyclonal Antibody (ARO-A14373)

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概述
货号ARO-A14373
品牌ProteoGenix
描述
Anti-LGALS8 Polyclonal Antibody (ARO-A14373) is a rabbit polyclonal antibody detecting PCTA-1, Po66 carbohydrate-binding protein, Po66-CBP, Galectin-8, Gal-8, LGALS8, Prostate carcinoma tumor antigen 1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human LGALS8 (Met2-Trp317).
靶标PCTA-1, Po66 carbohydrate-binding protein, Po66-CBP, Galectin-8, Gal-8, LGALS8, Prostate carcinoma tumor antigen 1
纯化方式Purified by antigen affinity column.
Accession号O00214
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Galectin-8 (GAL-8) is a ~35 kDa protein. Beta-galactoside-binding lectin that acts as a sensor of membrane damage caused by infection and restricts the proliferation of infecting pathogens by targeting them for autophagy. Detects membrane rupture by binding beta-galactoside ligands located on the lumenal side of the endosome membrane; these ligands becoming exposed to the cytoplasm following rupture. Restricts infection by initiating autophagy via interaction with CALCOCO2/NDP52. Required to restrict infection of bacterial invasion such as S.typhimurium. Also required to restrict infection of Picornaviridae viruses.

1. Thurston, TL. et al. (2012) Nature 482, 414-8. PMID: 22246324
2. Staring, J. et al. (2017) Nature 541, 412-416. PMID: 28077878
3. Ideo, H. et al. (2011) The Journal of biological chemistry 286, 11346-55. PMID: 21288902
NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-LGALS8 Polyclonal Antibody

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